SPR antibody (C-Term)

Catalog No. ABIN929291

Product Details anti-SPR Antibody

Target: SPR (Sepiapterin Reductase (SPR))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPR antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: SPR antibody was raised in rabbit using the C terminal of SPR as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SPR Blocking Peptide, catalog no. 33R-2771, is also available for use as a blocking control in assays to test for specificity of this SPR antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SPR

Target: SPR (Sepiapterin Reductase (SPR))

Alternative Name: SPR (SPR Products)

Synonyms: SDR38C1 antibody, AA409688 antibody, ENSMUSG00000071345 antibody, Gm10328 antibody, CG12117 antibody, Dmel\\CG12117 antibody, SR antibody, sptr antibody, xspr antibody, DDBDRAFT_0188686 antibody, DDBDRAFT_0191275 antibody, DDB_0188686 antibody, DDB_0191275 antibody, zgc:194446 antibody, sepiapterin reductase antibody, Sepiapterin reductase antibody, sepiapterin reductase L homeolog antibody, sepiapterin reductase b antibody, SPR antibody, Spr antibody, Sptr antibody, spr.L antibody, sprE antibody, CpipJ_CPIJ000511 antibody, sr antibody, spr antibody, sprb antibody

Background: This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. Synonyms: Polyclonal SPR antibody, Anti-SPR antibody, sepiapterin reductase, 7,8-dihydrobiopterin:NADP+ oxidoreductase antibody, SDR38C1 antibody.

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration