MCL-1 antibody

Catalog No. ABIN3210009

This Mouse Monoclonal antibody specifically detects MCL-1 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for MCL-1 antibody (ABIN3210009)

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MCL-1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 8C6-8C6D4B1

Product Details anti-MCL-1 Antibody

Purification: Purified antibody.

Immunogen: MCL1 antibody was raised in Mouse using a purified recombinant fragment of human MCL-1 expressed in E. coli as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Purified antibody supplied in PBS containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for MCL-1

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Alternative Name: MCL1

Background: MCL1 is a protein which belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing. Synonyms: Monoclonal MCL1 antibody, Anti-MCL1 antibody, MCL-1 antibody, MCL 1 antibody, Myeloid cell leukemia 1 antibody.

Pathways: MAPK Signaling