LDOC1 antibody

Catalog No. ABIN932190

Product Details anti-LDOC1 Antibody

Target: LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LDOC1 antibody is un-conjugated

Application: Dot Blot (DB)

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: LDOC1 antibody was raised in mouse using recombinant Human Leucine Zipper, Down-Regulated In Cancer 1 (Ldoc1)

Clone: 2507C1a

Isotype: IgG2a

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: LDOC1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for LDOC1

Target: LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))

Alternative Name: LDOC1 (LDOC1 Products)

Synonyms: BCUR1 antibody, Mar7 antibody, Mart7 antibody, RGD1565644 antibody, Gm366 antibody, LDOC1 antibody, LDOC1, regulator of NFKB signaling antibody, regulator of NFKB signaling antibody, LDOC1 antibody, Ldoc1 antibody

Background: The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. Synonyms: Monoclonal LDOC1 antibody, Anti-LDOC1 antibody, Leucine zipper down regulated in cancer 1 antibody, Mar7 antibody, BCUR1 antibody, Mart7 antibody.