MAP2K4 antibody

Catalog No. ABIN932745

The Mouse Monoclonal anti-MAP2K4 antibody (Clone 2D10D8-4G11B2-2D10C4-2D10C3) (ABIN932745) specifically detects MAP2K4 in IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for MAP2K4 antibody (ABIN932745)

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAP2K4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: 2D10D8-4G11B2-2D10C4-2D10C3

Product Details anti-MAP2K4 Antibody

Immunogen: MAP2 K4 antibody was raised in Mouse using a purified recombinant fragment of MAP2 4 expressed in E. coli as the immunogen.

Isotype: IgM

Application Details

Application Notes: ELISA: 1:10,000, IHC: 1:200-1:1000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for MAP2K4

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Alternative Name: MAP2K4

Background: MAP2K4 is a a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is adirect activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shownto activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. Synonyms: Monoclonal MAP2K4 antibody, Anti-MAP2K4 antibody, Mitogen-activated protein kinase kinase 4 antibody, MAPK/ERK kinase 4 antibody, MAPKK 4 antibody, SAPK/ERK kinase 1 antibody.

Pathways: MAPK Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling