Resistin antibody

Catalog No. ABIN934075

Product Details anti-Resistin Antibody

Target: Resistin (RETN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Resistin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Immunogen: Resistin antibody was raised in mouse using highly pure recombinant human resistin as the immunogen.

Clone: M912287

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for Resistin

Target: Resistin (RETN)

Alternative Name: Resistin (RETN Products)

Synonyms: RETN antibody, ADSF antibody, FIZZ3 antibody, RETN1 antibody, RSTN antibody, XCP1 antibody, Fizz3 antibody, Rstn antibody, Xcp4 antibody, resistin antibody, RETN antibody, Retn antibody

Background: Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family, Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Synonyms: Monoclonal Resistin antibody, Anti-Resistin antibody, FIZZ3 antibody, Adipose tissue-specific secretory factor antibody, ADSF antibody.

Molecular Weight: 20.2 kDa (predicted detection band MW)

Pathways: Feeding Behaviour, Smooth Muscle Cell Migration