Abcd2 antibody (Middle Region)

Catalog No. ABIN950204

Product Details anti-Abcd2 Antibody

Target: Abcd2 (ATP-Binding Cassette, Sub-Family D (ALD), Member 2 (Abcd2))

Binding Specificity: AA 276-306, Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Abcd2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to ABCD2.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 276~306 amino acids from the Central region of human ABCD2.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Abcd2

Target: Abcd2 (ATP-Binding Cassette, Sub-Family D (ALD), Member 2 (Abcd2))

Alternative Name: ABCD2 / ALDR (Abcd2 Products)

Synonyms: DDBDRAFT_0214891 antibody, DDBDRAFT_0219834 antibody, DDB_0214891 antibody, DDB_0219834 antibody, ABC39 antibody, ALDL1 antibody, ALDR antibody, ALDRP antibody, hALDR antibody, ATP binding cassette subfamily D member 2 antibody, ABC transporter D family protein antibody, ATP-binding cassette sub-family D member 2 antibody, ATP-binding cassette, sub-family D (ALD), member 2 antibody, ABCD2 antibody, abcD2 antibody, LOC100549247 antibody, abcd2 antibody, LOC100640478 antibody, Abcd2 antibody

Background: ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown, however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.Synonyms: ALD1, ALDL1, ALDRP, ATP-binding cassette sub-family D member 2, Adrenoleukodystrophy-like 1, Adrenoleukodystrophy-related protein

Gene ID: 225

NCBI Accession: NP_005155

Pathways: Monocarboxylic Acid Catabolic Process