Abcd2 Products
(ATP-Binding Cassette, Sub-Family D (ALD), Member 2 (Abcd2))
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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown\; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq, Jul 2008].
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Featured Abcd2 Categories
Abcd2 Antibodies
High quality antibodies with extensive validation data.
Recommended Abcd2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, ICC, IP
Validations
- (5)
Cat. No.
ABIN7445003
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN467567
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN2854625
Quantity
100 μL
Datasheet
Datasheet
Recommended Abcd2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6224893
Quantity
96 tests
Datasheet
Datasheet
Recommended Abcd2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419502
Quantity
100 μg
Datasheet
Datasheet
Synonyms and alternative names related to Abcd2
ATP binding cassette subfamily D member 2 (ABCD2), ABC transporter D family protein (abcD2), ATP-binding cassette sub-family D member 2 (LOC100549247), ATP binding cassette subfamily D member 2 (abcd2), ATP-binding cassette sub-family D member 2 (LOC100640478), ATP-binding cassette, sub-family D (ALD), member 2 (Abcd2), ATP binding cassette subfamily D member 2 (Abcd2), ABC39, ALDL1, ALDR, ALDRP, DDBDRAFT_0214891, DDBDRAFT_0219834, DDB_0214891, DDB_0219834, hALDRProtein level used designations for Abcd2
- ATP-binding cassette, sub-family D, member 2
- ATP-binding cassette, sub-family D (ALD), member 2
- ATP-binding cassette sub-family D member 2
- ATP-binding cassette sub-family D member 2-like
- adrenoleukodystrophy-like 1
- adrenoleukodystrophy-related protein
- adrenoleukodystrophy related
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