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ADA antibody (Adenosine Deaminase) (C-Term)

Details for Product anti-ADA Antibody No. ABIN950276, Supplier: Log in to see
Antigen
  • ADA
  • ADA-like
  • ADGDF-A
  • ADGF-A
  • adgf-a
  • Adgf-a
  • adgfa
  • CG5992
  • CG11994
  • dADA
  • Dmel\\CG5992
  • Dmel\\CG11994
  • DrosADA
  • xada
  • zgc:92028
Epitope
C-Term, AA 294-322
31
13
10
10
6
5
5
3
2
2
2
1
1
1
1
1
Reactivity
Human
105
38
27
24
1
1
1
Host
Rabbit
112
30
1
Clonality
Polyclonal
Conjugate
This ADA antibody is un-conjugated
13
6
5
3
3
3
2
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
116
73
20
19
15
15
13
12
5
5
4
3
3
3
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 294-322 amino acids from the C-terminal region of human ADA
Isotype Ig
Specificity This antibody reacts to Adenosine deaminase.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Background This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.Synonyms: Adenosine aminohydrolase
Gene ID 100
NCBI Accession NP_000013
Research Area Cell Cycle, DNA/RNA, Enzymes
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-ADA antibody (Adenosine Deaminase) (C-Term) (ABIN950276) ADA Antibody (C-term) flow cytometric analysis of HL-60 cells (right histogram) compa...
Western Blotting (WB) image for anti-ADA antibody (Adenosine Deaminase) (C-Term) (ABIN950276) ADA Antibody (C-term) western blot analysis in HL-60 cell line lysates (35 µg/lane).T...
Background publications Gloria-Bottini, Banci, Saccucci, Papetti, Neri, Pietroiusti, Magrini, Bottini: "The interaction of ACP1, ADA1, diabetes and gender in coronary artery disease." in: The American journal of the medical sciences, Vol. 340, Issue 2, pp. 103-8, 2010 (PubMed).

Levine, Figueiredo, Lee, Conti, Kennedy, Duggan, Poynter, Campbell, Newcomb, Martinez, Hopper, Le Marchand, Baron, Limburg, Ulrich, Haile: "A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 7, pp. 1812-21, 2010 (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).