ADCY2 antibody (Middle Region)

Catalog No. ABIN950278

This Rabbit Polyclonal antibody specifically detects ADCY2 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for ADCY2 antibody (Middle Region) (ABIN950278)

Target: ADCY2 (Adenylate Cyclase 2 (Brain) (ADCY2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ADCY2 Antibody

Binding Specificity: AA 458-489, Middle Region

Specificity: This antibody reacts to Adenylate cyclase type 2.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide between 458-489 amino acids from the Central region of human ADCY2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ADCY2

Target: ADCY2 (Adenylate Cyclase 2 (Brain) (ADCY2))

Alternative Name: Adenylate Cyclase Type 2

Background: This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.Synonyms: ADCY2, ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2, KIAA1060

Gene ID: 108

NCBI Accession: NP_065433

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma