You are viewing an incomplete version of our website. Please click to reload the website as full version.

ADCY2 antibody (Adenylate Cyclase 2 (Brain)) (AA 458-489)

Details for Product anti-ADCY2 Antibody No. ABIN950278, Supplier: Log in to see
Antigen
  • ADCY2
  • mKIAA1060
  • AC2
  • HBAC2
  • adenylate cyclase 2
  • adenylate cyclase 2 (brain)
  • ADCY2
  • Adcy2
Alternatives
anti-Human ADCY2 antibody for Enzyme Immunoassay
Epitope
AA 458-489, Middle Region
5
4
3
2
2
2
2
2
1
1
1
Reactivity
Human
26
6
5
Host
Rabbit
23
3
Clonality
Polyclonal
Conjugate
This ADCY2 antibody is un-conjugated
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
23
12
6
4
3
2
2
2
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen KLH conjugated synthetic peptide between 458-489 amino acids from the Central region of human ADCY2
Isotype Ig
Specificity This antibody reacts to Adenylate cyclase type 2.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Saturated Ammonium Sulfate (SAS) precipitation
Alternative Name Adenylate Cyclase Type 2 (ADCY2 Antibody Abstract)
Background This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.Synonyms: ADCY2, ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2, KIAA1060
Gene ID 108
NCBI Accession NP_065433
Pathways EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-ADCY2 antibody (Adenylate Cyclase 2 (Brain)) (AA 458-489) (ABIN950278) ADCY2 Antibody (Center) western blot analysis in Jurkat cell line lysates (35 µg/lane...
Background publications Halls, Cooper: "Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex." in: The EMBO journal, Vol. 29, Issue 16, pp. 2772-87, 2010 (PubMed).

Need, Keefe, Ge, Grossman, Dickson, McEvoy, Goldstein: "Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis." in: European journal of human genetics : EJHG, Vol. 17, Issue 7, pp. 946-57, 2009 (PubMed).

Uhl, Liu, Drgon, Johnson, Walther, Rose, David, Niaura, Lerman: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).

Sunahara, Taussig: "Isoforms of mammalian adenylyl cyclase: multiplicities of signaling." in: Molecular interventions, Vol. 2, Issue 3, pp. 168-84, 2004 (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, 1996 (PubMed).