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Anterior Gradient 3 Homolog (Xenopus Laevis) (AGR3) (AA 126-155), (C-Term) antibody

Details for Product No. ABIN950305, Supplier: Log in to see
Antigen
  • AG3
  • BCMP11
  • HAG3
  • PDIA18
  • hAG-3
  • E030025L21Rik
  • Gm888
  • LFA-3
  • LFA3
  • ag3
Epitope
AA 126-155, C-Term
17
15
4
4
2
2
2
1
1
Reactivity
Human
59
11
3
Host
Rabbit
44
15
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
46
38
29
18
14
13
13
9
1
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 126~155 amino acids from the C-terminal region of Human AGR3
Isotype Ig
Specificity This antibody recognizes Human AGR3 (C-term).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Protein A column, followed by peptide affinity purification
Alternative Name AGR3 (AGR3 Antibody Abstract)
Background AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.Synonyms: Anterior gradient protein 3 homolog, BCMP11, HAG-3, HAG3, breast cancer membrane protein 11
Gene ID 155465
NCBI Accession NP_789783
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Anterior Gradient 3 Homolog (Xenopus Laevis) (AGR3) (AA 126-155), (C-Term) antibody (ABIN950305) AGR3 Antibody (C-term) flow cytometry analysis of MCF-7 cells (bottom histogram) comp...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Anterior Gradient 3 Homolog (Xenopus Laevis) (AGR3) (AA 126-155), (C-Term) antibody (ABIN950305) Formalin-fixed and paraffin-embedded human lung carcinoma reacted with AGR3 Antibody ...
Western Blotting (WB) image for anti-Anterior Gradient 3 Homolog (Xenopus Laevis) (AGR3) (AA 126-155), (C-Term) antibody (ABIN950305) Western blot analysis of AGR3 Antibody (C-term) in MCF-7 cell line lysates (35µg/lane...
Background publications Persson, Rosenquist, Knoblach et al.: "Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family." in: Molecular phylogenetics and evolution, Vol. 36, Issue 3, pp. 734-40, 2005 (PubMed).

Zhang, Henzel: "Signal peptide prediction based on analysis of experimentally verified cleavage sites." in: Protein science : a publication of the Protein Society, Vol. 13, Issue 10, pp. 2819-24, 2004 (PubMed).

Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Fletcher, Patel, Tyson et al.: "hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan." in: British journal of cancer, Vol. 88, Issue 4, pp. 579-85, 2003 (PubMed).