You are viewing an incomplete version of our website. Please click to reload the website as full version.

Anterior Gradient 3 Homolog (Xenopus Laevis) (AGR3) (AA 126-155), (C-Term) antibody

Details for Product No. ABIN950305, Supplier: Log in to see
Antigen
  • AG3
  • ag3
  • BCMP11
  • E030025L21Rik
  • Gm888
  • hAG-3
  • HAG3
  • LFA-3
  • LFA3
  • PDIA18
Epitope
AA 126-155, C-Term
17
15
4
4
2
2
2
1
1
Reactivity
Human
59
11
3
Host
Rabbit
44
15
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
46
38
29
18
14
13
13
7
3
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen KLH conjugated synthetic peptide between 126~155 amino acids from the C-terminal region of Human AGR3
Isotype Ig
Specificity This antibody recognizes Human AGR3 (C-term).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Protein A column, followed by peptide affinity purification
Alternative Name AGR3 (AGR3 Antibody Abstract)
Background AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.Synonyms: Anterior gradient protein 3 homolog, BCMP11, HAG-3, HAG3, breast cancer membrane protein 11
Gene ID 155465
NCBI Accession NP_789783
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Anterior Gradient 3 Homolog (Xenopus Laevis) (AGR3) (AA 126-155), (C-Term) antibody (ABIN950305) AGR3 Antibody (C-term) flow cytometry analysis of MCF-7 cells (bottom histogram) comp...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Anterior Gradient 3 Homolog (Xenopus Laevis) (AGR3) (AA 126-155), (C-Term) antibody (ABIN950305) Formalin-fixed and paraffin-embedded human lung carcinoma reacted with AGR3 Antibody ...
Western Blotting (WB) image for anti-Anterior Gradient 3 Homolog (Xenopus Laevis) (AGR3) (AA 126-155), (C-Term) antibody (ABIN950305) Western blot analysis of AGR3 Antibody (C-term) in MCF-7 cell line lysates (35µg/lane...
Background publications Persson, Rosenquist, Knoblach, Khosravi-Far, Sommarin, Michalak: "Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family." in: Molecular phylogenetics and evolution, Vol. 36, Issue 3, pp. 734-40, 2005 (PubMed).

Zhang, Henzel: "Signal peptide prediction based on analysis of experimentally verified cleavage sites." in: Protein science : a publication of the Protein Society, Vol. 13, Issue 10, pp. 2819-24, 2004 (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Fletcher, Patel, Tyson, Adam, Schenker, Loader, Daviet, Legrain, Parekh, Harris, Terrett: "hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan." in: British journal of cancer, Vol. 88, Issue 4, pp. 579-85, 2003 (PubMed).