anti-AKR1C4 antibody (Aldo-keto Reductase Family 1 Member C4) (N-Term)

Details for Product anti-AKR1C4 Antibody No. ABIN950323
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Antigen
Synonyms 3-alpha-HSD, C11, CDR, CHDR, DD-4, DD4, HAKRA
Epitope
N-Term, AA 10-39
(31), (15), (5), (5), (3), (2), (1)
Reactivity
Human
(70), (6), (6)
Host
Rabbit
(36), (21), (12), (1)
Clonality
Polyclonal
Conjugate
This AKR1C4 antibody is un-conjugated
(3), (3), (3), (3), (3), (3)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(67), (38), (19), (11), (10), (4), (3), (3), (2), (1), (1)
Pubmed 2 references available
Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Immunogen KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human AKR1C4.
Isotype Ig
Specificity This antibody reacts to AKR1C4.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name AKR1C4 (AKR1C4 Antibody Abstract)
Background AKR1C4 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.Synonyms: 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, Aldo-keto reductase family 1 member C4, CDR, CHDR, Chlordecone reductase, DD-4, DD4, Dihydrodiol dehydrogenase 4, HAKRA
Gene ID 1109
NCBI Accession NP_001809
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Joslyn, Ravindranathan, Brush et al.: "Human variation in alcohol response is influenced by variation in neuronal signaling genes." in: Alcoholism, clinical and experimental research, Vol. 34, Issue 5, pp. 800-12, 2010 (PubMed).

Guey, García-Closas, Murta-Nascimento et al.: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, 2010 (PubMed).

Validation Images
Catalog No. ABIN950323
357.50 $
Plus shipping costs $45.00
Quantity
Price
0.4 mL
357.50 $

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