Actin antibody (C-Term)
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- Target See all Actin (ACTA1) Antibodies
- Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
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Binding Specificity
- AA 345-376, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Actin antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody reacts to alpha skeletal muscle Actin.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity chromatography on Protein A
- Immunogen
- KLH conjugated synthetic peptide between 345-376 amino acids from the C-terminal region of human ACTA1/alpha-actin
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ACTA1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) sodium azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
- Alternative Name
- alpha Skeletal Muscle Actin / ACTA1 (ACTA1 Products)
- Background
- The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
- Gene ID
- 58
- NCBI Accession
- NP_001091
- Pathways
- Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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