rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5) (C-Term), (AA 1502-1530) antibody

Details for Product No. ABIN950496
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Antigen
Synonyms ARHGEF5, GEF5, P60, TIM, TIM1, 2210412D05Rik, AA717842, AW495314, Tim1
Epitope
C-Term, AA 1502-1530
(9), (7), (7), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(44), (14), (14)
Host
Rabbit
(34), (5), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(41), (27), (5), (4), (4), (4), (2), (1)
Pubmed 3 references available
Quantity 0.4 mL
Shipping to United States (Change)
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Catalog No. ABIN950496
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Immunogen KLH conjugated synthetic peptide between 1502-1530 amino acids from the C-terminal region of human ARHGEF5
Specificity This antibody reacts to ARHGEF5.
Purification Affinity chromatography on Protein A
Alternative Name ARHGEF5 / TIM
Background Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.
Alternate names: Guanine nucleotide regulatory protein TIM, Oncogene TIM, Rho guanine nucleotide exchange factor 5, Transforming immortalized mammary oncogene, p60 TIM
Gene ID 7984
NCBI Accession NP_005426
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Zhang, Wolf-Yadlin, Ross et al.: "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 9, pp. 1240-50, 2005 (PubMed).

Lin, Chang, Yeh et al.: "Disturbance of circadian gene expression in hepatocellular carcinoma." in: Molecular carcinogenesis, Vol. 47, Issue 12, pp. 925-33, 2008 (PubMed).

Wang, Kumamoto, Wang et al.: "Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5." in: The Journal of biological chemistry, Vol. 284, Issue 42, pp. 28599-606, 2009 (PubMed).

Validation Images
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