BCL2-Associated Athanogene 5 (BAG5) (N-Term), (AA 20-50) antibody

Details for Product No. ABIN950599
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Antigen
Synonyms BAG5, zgc:114117, bag-5, BAG-5, 1600025G07Rik, 4930405J06Rik
Epitope
N-Term, AA 20-50
(16), (7), (7), (7), (4), (2), (1), (1), (1), (1)
Reactivity
Human
(74), (24), (24), (16), (12), (5), (3)
Host
Rabbit
(53), (17), (7)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(58), (31), (12), (10), (5), (4), (4), (2), (2), (2), (1)
Pubmed 3 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN950599
357.50 $
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Immunogen KLH conjugated synthetic peptide between 20-50 amino acids from the N-terminal region of human BAG5
Isotype Ig
Specificity This antibody reacts to BAG5.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name BAG5
Background BAG5 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.Synonyms: BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5, KIAA0873
Gene ID 9529
NCBI Accession NP_001015048
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Höhfeld, Jentsch: "GrpE-like regulation of the hsc70 chaperone by the anti-apoptotic protein BAG-1." in: The EMBO journal, Vol. 16, Issue 20, pp. 6209-16, 1997 (PubMed).

Takayama, Xie, Reed: "An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 781-6, 1999 (PubMed).

Zhou, Deng, Xia et al.: "Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition." in: Nature cell biology, Vol. 6, Issue 10, pp. 931-40, 2004 (PubMed).

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