BSD Domain Containing 1 (BSDC1) (C-Term), (AA 396-425) antibody

Details for Product No. ABIN950682
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Antigen
Synonyms AW011758, 1110063F24Rik, RGD1311622, fb51h12, wu:fb51h12, zgc:100785, bsdc1, BSDC1
Epitope
C-Term, AA 396-425
(3), (2), (2), (1)
Reactivity
Human
(7), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(7), (1)
Clonality
Polyclonal
Application
ELISA, Western Blotting (WB)
(8), (3), (1)
Pubmed 3 references available
Catalog no. ABIN950682
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days

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Immunogen KLH conjugated synthetic peptide between 396-425 amino acids from the C-terminal region of human BSDC1
Specificity This antibody reacts to BSDC1.
Purification Affinity chromatography on Protein A
Alternative Name BSDC1
Background BSDC1 is a 430 amino acid protein encoded by a gene mapping to chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Alternate names: BSD domain-containing protein 1
Gene ID 55108
NCBI Accession NP_060515
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) sodium azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment...." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Fu, Wang, Yang et al.: "Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes." in: Genomics, Vol. 84, Issue 1, pp. 205-10, 2004 (PubMed).

Oh, Yang, Hahn et al.: "Transcriptome analysis of human gastric cancer." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 16, Issue 12, pp. 942-54, 2005 (PubMed).

Hosts (7), (1)
Reactivities (7), (1), (1), (1), (1), (1), (1)
Applications (8), (3), (1)
Epitopes (3), (2), (2), (1)
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