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- Target See all C5AR1 Antibodies
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
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Reactivity
- Human
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This C5AR1 antibody is conjugated to Biotin
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Application
- Flow Cytometry (FACS)
- Specificity
- This monoclonal antibody detects an epitope on the N terminus (aa 1-15) of the human C5a receptor (also known as CD88) found on human myeloid cells including granulocytes and monocytes/macrophages. It does not bind to tubular epithelial cells in situ under normal or inflammatory conditions. C5aR binds to C5a, a 74 aa peptide cleaved from complement protein C5. C5a receptor has seven transmembrane segments and is a member of the rhodopsin subfamily of G protein coupled receptors.
- Purification
- Affinity chromatography on Protein G
- Immunogen
- RBL-2H3 (rat basophilic leukemia) transfected cells expressing human C5aR on the cell surface Donor: Lou/c rat spleen cells
- Clone
- 8D6
- Isotype
- IgG2a
- Top Product
- Discover our top product C5AR1 Primary Antibody
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anti-Complement Component 5a Receptor 1 (C5AR1) (C-Term) antibody
Verified C5AR1 Reactivity: Human WB, FACS, ELISA, IHC, IF Host: Goat Polyclonal unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 15-27) antibodyC5AR1 Reactivity: Human, Cow, Rabbit, Ferret WB, FACS, IHC (p), IP Host: Mouse Monoclonal S5-1 unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 1-350) antibodyC5AR1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4E2 unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 250-350) antibodyC5AR1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 1-36) antibodyC5AR1 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 15-27) antibody (FITC)C5AR1 Reactivity: Human, Cow, Rabbit, Ferret FACS Host: Mouse Monoclonal S5-1 FITC
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 175-201) antibodyC5AR1 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB24276 unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) antibodyC5AR1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 15-27) antibody (APC)C5AR1 Reactivity: Human, Cow, Rabbit, Ferret FACS Host: Mouse Monoclonal S5-1 APC
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 15-27) antibody (PE)C5AR1 Reactivity: Human, Cow, Rabbit, Ferret FACS Host: Mouse Monoclonal S5-1 PE
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0,1 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide (NaN3) as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
- Alternative Name
- CD88 / C5R1 (C5AR1 Products)
- Synonyms
- C5A antibody, C5AR antibody, C5R1 antibody, CD88 antibody, C5aR antibody, C5r1 antibody, Cd88 antibody, D7Msu1 antibody, GPR77 antibody, complement C5a receptor 1 antibody, complement component 5a receptor 1 antibody, C5AR1 antibody, C5ar1 antibody, c5ar1 antibody
- Background
- Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1
- Gene ID
- 728
- NCBI Accession
- NP_001727
- UniProt
- P21730
- Pathways
- Complement System
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