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CD90 antibody (THY1) (APC)

Details for Product anti-THY1 Antibody No. ABIN951435, Supplier: Log in to see
Antigen
  • CD7
  • CD90
  • T25
  • Thy-1
  • Thy-1.2
  • Thy1.1
  • Thy1.2
Reactivity
Mouse (Murine)
352
337
145
42
40
28
26
24
22
21
10
5
4
4
2
2
1
Host
Mouse
417
203
97
17
1
Clonality (Clone)
Monoclonal ()
Conjugate
This CD90 antibody is conjugated to APC
82
74
58
31
14
14
11
11
9
8
8
7
7
7
7
7
6
5
4
4
4
4
3
3
3
3
3
2
2
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
543
207
173
145
114
83
75
71
36
32
25
13
9
9
8
6
5
3
2
2
1
1
Supplier
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Immunogen CBA/J. Donor: AKR/J Spleen. Fusion Partner: Spleen from immunized recipient fused with myeloma P3-NSI-1-Ag4-1.
Clone 5a-8
Isotype IgG2b
Specificity This monoclonal antibody reacts with all T lymphocytes from mouse strains expressing the Thy 1.2 phenotype (e.g. C57BL/6, C3H/He, DBA/2, CBA/J, BALB/c), but does not react with lymphocytes expressing the Thy 1.1 phenotype [e.g. AKR/J, B6.PL(74NS)].
Alternative Name CD90 (THY1 Antibody Abstract)
Background CD90 (Thy1) antigen is a GPI linked glycoprotein member of the Immunoglobulin superfamily. It is expressed on murine T cells, thymocytes, neural cells, cells of granulocytic lineage, early hematopoietic progenitors, fibroblasts, neurons and Kupffer's cells. Thy1 may play a role in cell to cell or cell to ligand interactions during synaptogenesis and other events in the brain. It is found in most mouse strains except AKR/J, A, Thy1.1 and B6.PL (74NS) expressing Thy1.1.Synonyms: CDw90, THY1, Thy-1, Thy-1 membrane glycoprotein
Gene ID 21838
NCBI Accession NP_033408
UniProt P01831
Research Area CD Antigens, Surface Receptors of Immune Cells, Experimental Models
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Background publications Radrizzani, Carminatti, Pivetta, Idoyaga Vargas: "Developmental regulation of Thy 1.2 rate of synthesis in the mouse cerebellum." in: Journal of neuroscience research, Vol. 42, Issue 2, pp. 220-7, 1996 (PubMed).

Krieg, Gourley, Steinberg: "Association of murine lupus and thymic full-length endogenous retroviral expression maps to a bone marrow stem cell." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 146, Issue 9, pp. 3002-5, 1991 (PubMed).

Haba, Nisonoff: "Induction of tolerance to syngeneic IgE in neonatal mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 146, Issue 3, pp. 807-11, 1991 (PubMed).

Kruger, Riley: "The age-dependent loss of bone marrow B cell precursors in autoimmune NZ mice results from decreased mitotic activity, but not from inherent stromal cell defects." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 1, pp. 103-10, 1990 (PubMed).

Fine, Silverstone, Gasiewicz: "Impairment of prothymocyte activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 4, pp. 1169-76, 1990 (PubMed).

Ledbetter, Rouse, Micklem, Herzenberg: "T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views." in: The Journal of experimental medicine, Vol. 152, Issue 2, pp. 280-95, 1980 (PubMed).