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CD90 antibody (THY1) (APC)

Details for Product anti-THY1 Antibody No. ABIN951435, Supplier: Log in to see
Antigen
  • CD90
  • CD7
  • T25
  • Thy-1
  • Thy-1.2
  • Thy1.1
  • Thy1.2
Reactivity
Mouse (Murine)
273
244
123
28
26
25
17
17
10
5
4
4
3
2
2
1
Host
Mouse
288
191
97
15
Clonality (Clone)
Monoclonal ()
Conjugate
This CD90 antibody is conjugated to APC
56
46
43
28
5
5
5
5
5
5
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
416
142
101
93
73
59
36
30
27
26
12
10
9
9
5
4
3
2
2
1
Supplier
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Immunogen CBA/J. Donor: AKR/J Spleen. Fusion Partner: Spleen from immunized recipient fused with myeloma P3-NSI-1-Ag4-1.
Clone 5a-8
Isotype IgG2b
Specificity This monoclonal antibody reacts with all T lymphocytes from mouse strains expressing the Thy 1.2 phenotype (e.g. C57BL/6, C3H/He, DBA/2, CBA/J, BALB/c), but does not react with lymphocytes expressing the Thy 1.1 phenotype [e.g. AKR/J, B6.PL(74NS)].
Alternative Name CD90 (THY1 Antibody Abstract)
Background CD90 (Thy1) antigen is a GPI linked glycoprotein member of the Immunoglobulin superfamily. It is expressed on murine T cells, thymocytes, neural cells, cells of granulocytic lineage, early hematopoietic progenitors, fibroblasts, neurons and Kupffer's cells. Thy1 may play a role in cell to cell or cell to ligand interactions during synaptogenesis and other events in the brain. It is found in most mouse strains except AKR/J, A, Thy1.1 and B6.PL (74NS) expressing Thy1.1.Synonyms: CDw90, THY1, Thy-1, Thy-1 membrane glycoprotein
Gene ID 21838
NCBI Accession NP_033408
UniProt P01831
Research Area CD Antigens, Surface Receptors of Immune Cells, Experimental Models
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Background publications Radrizzani, Carminatti, Pivetta et al.: "Developmental regulation of Thy 1.2 rate of synthesis in the mouse cerebellum." in: Journal of neuroscience research, Vol. 42, Issue 2, pp. 220-7, 1996 (PubMed).

Ledbetter, Rouse, Micklem et al.: "T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views." in: The Journal of experimental medicine, Vol. 152, Issue 2, pp. 280-95, 1980 (PubMed).

Fine, Silverstone, Gasiewicz: "Impairment of prothymocyte activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 4, pp. 1169-76, 1990 (PubMed).

Kruger, Riley: "The age-dependent loss of bone marrow B cell precursors in autoimmune NZ mice results from decreased mitotic activity, but not from inherent stromal cell defects." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 1, pp. 103-10, 1990 (PubMed).

Krieg, Gourley, Steinberg: "Association of murine lupus and thymic full-length endogenous retroviral expression maps to a bone marrow stem cell." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 146, Issue 9, pp. 3002-5, 1991 (PubMed).

Haba, Nisonoff: "Induction of tolerance to syngeneic IgE in neonatal mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 146, Issue 3, pp. 807-11, 1991 (PubMed).