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Details for Product No. ABIN951473

Centractin alpha (AA 97-126), (Middle Region) antibody

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Antigen
Epitope
»Alternatives AA 97-126, Middle Region
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN951473
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human ACTR1A
Specificity This antibody reacts to Centractin alpha.
Purification Affinity chromatography on Protein A
Background This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to- Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
Alternate names: ACTR1A, ARP1, Actin-RPV, CTRN1, Centrosome-associated actin homolog
Gene ID 10121
NCBI Accession NP_005727
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) sodium azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Petretti, Savoian, Montembault et al.: "The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation." in: EMBO reports, Vol. 7, Issue 4, pp. 418-24, 2006 (PubMed).

Sugarbaker, Richards, Gordon et al.: "Transcriptome sequencing of malignant pleural mesothelioma tumors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 9, pp. 3521-6, 2008 (PubMed).

Alternatives for antigen "Centractin alpha", type "Antibodies"
Hosts (1)
Reactivities (1), (1), (1), (1)
Applications (1)
Epitopes (1)
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