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Chondroadherin-Like (CHADL) (AA 405-434), (Middle Region) antibody

Details for Product No. ABIN951491, Supplier: Login to see
Antigen
  • SLRR4B
Epitope
AA 405-434, Middle Region
15
13
10
2
Reactivity
Human
18
Host
Rabbit
18
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
16
14
Supplier
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Immunogen KLH conjugated synthetic peptide between 405-434 amino acids from the Central region of human CHADL
Isotype Ig
Specificity This antibody reacts to CHADL.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name CHADL
Background Members of the small leucine-rich proteoglycan (SLRP) family are mostly extracellular proteins that function upstream of multiple signaling cascades. They affect intracellular phosphorylation and modulate distinct pathways, such as those driven by Toll-like receptors, TGF? and receptor tyrosine kinases. As a member of the SLRP family, CHADL (Chondroadherin-like protein) is a 762 amino acid protein containing 21 LRR (leucine-rich) repeats, which promote protein-ligand interactions. Chondroadherin, a closely related protein, promotes attachment of chrondocytes, osteoblasts and fibroblasts and also plays an important role in the regulation of chrodrocyte proliferation and growth. CHADL is a secreted protein that is located in the extracellular space. There are two isoforms of CHADL that exist as a result of alternative splicing events.Synonyms: Chondroadherin-like protein, SLRR4B
Molecular Weight Isoform2 74kd. 82388 Da
Gene ID 150356
NCBI Accession NP_612490
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Chondroadherin-Like (CHADL) (AA 405-434), (Middle Region) antibody (ABIN951491) CHADL Antibody (Center) western blot analysis in T47D cell line lysates (35µg/lane).T...
Background publications Barbe, Lundberg, Oksvold et al.: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).