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Coilin antibody (Middle Region)
COIL
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Coilin Antibody
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Target
See all Coilin (COIL) Antibodies
Coilin (COIL)
Binding Specificity
All epitopes for Coilin antibodies
AA 156-186, Middle Region
Reactivity
All reactivities for Coilin antibodies
Human
Host
All hosts for Coilin antibodies
Rabbit
Clonality
All clonalities for Coilin antibodies
Polyclonal
Conjugate
All conjugates for Coilin antibodies
This Coilin antibody is un-conjugated
Application
All applications for Coilin antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to COIL.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Affinity chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 156-186 amino acids from the Central region of human COIL
Isotype
Ig Fraction
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Discover our top product COIL Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Coilin
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Target
Coilin (COIL)
Alternative Name
Coilin (COIL Products )
Synonyms
p80c antibody, coil antibody, CG8710 antibody, Coilin antibody, Dmel\\CG8710 antibody, LOC100218802 antibody, F3F19.5 antibody, F3F19_5 antibody, CLN80 antibody, p80-coilin antibody, C79982 antibody, Cln80 antibody, p80 antibody, wu:fb08h11 antibody, sph1 antibody, Coilin antibody, coilin antibody, sphere organelles protein-like protein antibody, coilin p80 antibody, coilin L homeolog antibody, p80c antibody, COIL antibody, coil antibody, AT1G13030 antibody, Coil antibody, coil.L antibody
Background
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.Synonyms: CLN80, COIL, p80
Molecular Weight
62608 Da
Gene ID
8161
NCBI Accession
NP_004636
Pathways
Ribonucleoprotein Complex Subunit Organization
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