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CUZD1 antibody (CUB and Zona Pellucida-Like Domains 1) (C-Term)

Details for Product anti-CUZD1 Antibody No. ABIN951734, Supplier: Log in to see
Antigen
  • ERG-1
  • Erg-1
  • ERG1
  • Itmap1
  • Uo
  • Uo-44
  • UO-44
  • Usg
  • Utczp
Epitope
C-Term, AA 586-614
17
15
6
4
4
2
Reactivity
Human
25
4
4
Host
Rabbit
32
1
Clonality
Polyclonal
Conjugate
This CUZD1 antibody is un-conjugated
5
5
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
27
24
16
10
10
6
4
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 586-614 amino acids from the C-terminal region of human CUZD1
Isotype Ig
Specificity This antibody reacts to CUZD1.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name CUZD1 (CUZD1 Antibody Abstract)
Background Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2. May play an important role in the regulation of cell growth when overexpressed in colon adenocarcinoma LoVo cells. Traps Ca(2+)/calmodulin on CAMK2.Synonyms: CUB and ZP domain-containing protein 1, CUB and zona pellucida-like domain-containing protein 1
Molecular Weight 68153 Da, Isoform 36kd Da
Gene ID 50624
NCBI Accession NP_071317
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunofluorescence (IF) image for anti-CUZD1 antibody (CUB and Zona Pellucida-Like Domains 1) (C-Term) (ABIN951734) Confocal immunofluorescent analysis of CUZD1 Antibody (C-term)(Cat#AP51141PU-N) with ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CUZD1 antibody (CUB and Zona Pellucida-Like Domains 1) (C-Term) (ABIN951734) CUZD1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin ...
Western Blotting (WB) image for anti-CUZD1 antibody (CUB and Zona Pellucida-Like Domains 1) (C-Term) (ABIN951734) CUZD1 Antibody (C-term) western blot analysis in 293 cell line lysates (35µg/lane).Th...
Background publications Leong, Ong, Tay, Huynh: "Silencing expression of UO-44 (CUZD1) using small interfering RNA sensitizes human ovarian cancer cells to cisplatin in vitro." in: Oncogene, Vol. 26, Issue 6, pp. 870-80, 2007

Blanchetot, Chagnon, Dubé, Hallé, Tremblay: "Substrate-trapping techniques in the identification of cellular PTP targets." in: Methods (San Diego, Calif.), Vol. 35, Issue 1, pp. 44-53, 2004

Leong, Ng, Ong, Ng, Ma, Nguyen, Tay, Huynh: "Molecular cloning, characterization and isolation of novel spliced variants of the human ortholog of a rat estrogen-regulated membrane-associated protein, UO-44." in: Oncogene, Vol. 23, Issue 33, pp. 5707-18, 2004

Deloukas, Earthrowl, Grafham, Rubenfield, French, Steward, Sims, Jones, Searle, Scott, Howe, Hunt, Andrews, Gilbert, Swarbreck, Ashurst, Taylor, Battles, Bird, Ainscough, Almeida, Ashwell, Ambrose et al.: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003