PPIF antibody (Middle Region)

Catalog No. ABIN951771

Product Details anti-PPIF Antibody

Target: PPIF (Peptidylprolyl Isomerase F (PPIF))

Binding Specificity: AA 102-131, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIF antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Cyclophilin F (Center).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 102-131 amino acids from the Central region of Human Cyclophilin F. Genename: PPIF

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PPIF

Target: PPIF (Peptidylprolyl Isomerase F (PPIF))

Alternative Name: Cyclophilin F (PPIF Products)

Synonyms: CYP3 antibody, CyP-M antibody, Cyp-D antibody, CypD antibody, CyP-D antibody, ppif antibody, wu:fd61c06 antibody, zgc:101753 antibody, AW457192 antibody, CyP-F antibody, PPIase antibody, Cyp-40 antibody, cypf antibody, peptidylprolyl isomerase F antibody, peptidylprolyl isomerase Fa antibody, peptidylprolyl isomerase F (cyclophilin F) antibody, peptidylprolyl isomerase D antibody, peptidylprolyl isomerase F L homeolog antibody, PPIF antibody, ppifa antibody, Ppif antibody, Ppid antibody, ppif antibody, ppif.L antibody

Background: PPIF is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.Synonyms: CYP3, PPIF, PPIase F, Rotamase F, mitochondrial Peptidyl-prolyl cis-trans isomerase

Molecular Weight: 22040 Da

Gene ID: 10105

NCBI Accession: NP_005720

Pathways: Proton Transport, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity