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DEF6 antibody (Differentially Expressed in FDCP 6 Homolog (Mouse)) (C-Term)

Details for Product anti-DEF6 Antibody No. ABIN951875, Supplier: Login to see
Antigen
  • DEF6
  • Def6
  • zgc:63721
  • ibp
  • slat
  • swap70l
  • MGC68775
  • 2410003F05Rik
  • 6430538D02Rik
  • AV094905
  • Ibp
  • Slat
  • Slat2
  • Slat6
  • IBP
  • SLAT
  • SWAP70L
Epitope
C-Term, AA 499-528
24
15
6
4
2
2
2
2
1
Reactivity
Human
66
10
9
4
3
3
2
2
2
1
Host
Rabbit
33
27
8
Clonality
Polyclonal
Conjugate
This DEF6 antibody is un-conjugated
2
2
2
2
2
2
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
51
31
13
11
9
2
2
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 499-528 amino acids from the C-terminal region of human DEF6
Isotype Ig
Specificity This antibody recognizes Human DEF6 (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name DEF6 (DEF6 Antibody Abstract)
Background DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).Synonyms: DEF-6, Differentially expressed in FDCP 6 homolog, IBP, IRF4-binding protein, SLAT, SWAP70L
Molecular Weight 73910 Da
Gene ID 50619
NCBI Accession NP_071330
Research Area Signaling
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-DEF6 antibody (Differentially Expressed in FDCP 6 Homolog (Mouse)) (C-Term) (ABIN951875) western blot analysis of DEF6 Antibody (C-term) in A375 cell line lysates (35ug/lane)...
Background publications Zhao, Li, Bradfield et al.: "The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature." in: BMC medical genetics, Vol. 11, pp. 96, 2010 (PubMed).

Han, Lan, Park et al.: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, 2010 (PubMed).

Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).

Rajaraman, Brenner, Butler et al.: "Common variation in genes related to innate immunity and risk of adult glioma." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 5, pp. 1651-8, 2009 (PubMed).