LIG3 antibody (C-Term)

Catalog No. ABIN951931

Product Details anti-LIG3 Antibody

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Binding Specificity: AA 792-822, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIG3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human DNA ligase 3 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 792-822 amino acids from the C-terminal region of Human DNA ligase 3 Genename: LIG3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for LIG3

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Alternative Name: DNA Ligase 3 (LIG3 Products)

Synonyms: orf36 antibody, DDBDRAFT_0218523 antibody, DDBDRAFT_0232266 antibody, DDB_0218523 antibody, DDB_0232266 antibody, LIG3 antibody, wu:fb12c02 antibody, wu:fd10b03 antibody, wu:fm79b09 antibody, LIG2 antibody, D11Wsu78e antibody, An02g06890 antibody, AO090003000668 antibody, lig3 antibody, DNA ligase III antibody, BRCT domain-containing protein antibody, DNA ligase 3 antibody, ligase III, DNA, ATP-dependent antibody, ligase III, DNA, ATP-dependent L homeolog antibody, orf36 antibody, lig3 antibody, LIG3 antibody, Lig3 antibody, Bm1_22840 antibody, ANI_1_2644024 antibody, AOR_1_1174154 antibody, LOC100634887 antibody, lig3.L antibody

Background: This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: DNA ligase 3, DNA ligase III, EC=6.5.1.1, LIG-3, LIG3, Polydeoxyribonucleotide synthase [ATP] 3

Molecular Weight: 112907 Da

Gene ID: 3980

NCBI Accession: NP_002302

Pathways: DNA Damage Repair