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Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) (AA 467-495), (Middle Region) antibody

Details for Product No. ABIN952082, Supplier: Log in to see
Antigen
  • ecgp
  • gp96
  • tra1
  • grp94
  • DDBDRAFT_0206450
  • DDBDRAFT_0215015
  • DDB_0206450
  • DDB_0215015
  • TRA1
  • HSP90B1
  • ERp99
  • GRP94
  • TA-3
  • Targ2
  • Tra-1
  • Tra1
  • endoplasmin
  • GP96
  • fb61d09
  • tra-1
  • wu:fb61d09
  • wu:fq25g01
  • Grp94
  • ECGP
  • Gp96
  • ppk98
  • hsp108
  • heat shock protein 90kDa beta (Grp94), member 1
  • heat shock protein Hsp90 family protein
  • 94 kD glucose-regulated protein
  • glucose-regulated protein
  • glucose-regulated protein GRP94
  • heat shock protein 90, beta (Grp94), member 1
  • heat shock protein 90, beta (grp94), member 1
  • heat shock protein 90, beta, member 1
  • hsp90b1
  • grp94
  • HSP90B1
  • GRP94
  • LOC100009456
  • Hsp90b1
Alternatives
anti-Human Heat Shock Protein 90kDa beta (Grp94), Member 1 antibody for Immunofluorescence
Epitope
AA 467-495, Middle Region
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20
15
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11
9
5
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Reactivity
Human
302
186
153
106
69
69
62
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54
4
3
3
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Host
Rabbit
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Clonality
Polyclonal
Conjugate
Un-conjugated
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4
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2
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1
1
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1
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1
1
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1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
275
140
108
102
89
86
75
71
13
7
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5
3
1
Options
Supplier
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Immunogen KLH conjugated synthetic peptide between 467-495 amino acids from the Central region of human HSP90B1
Isotype Ig
Specificity This antibody recognizes Human Endoplasmin / HSP90B1 / TRA1 (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name Endoplasmin / HSP90B1 / TRA1 (HSP90B1 Antibody Abstract)
Background HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is an endoplasmic reticulum HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1, MIM 140571) and mitochondria (TRAP1, MIM 606219) (Chen et al., 2005 [PubMed 16269234]).Synonyms: 94 kDa glucose-regulated protein, GRP94, Heat shock protein 90 kDa beta member 1, Tumor rejection antigen 1
Molecular Weight 92469 Da
Gene ID 7184
NCBI Accession NP_003290
Pathways Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) (AA 467-495), (Middle Region) antibody (ABIN952082) Flow cytometric analysis of A549 cells using Endoplasmin / HSP90B1 / TRA1 Antibody (C...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) (AA 467-495), (Middle Region) antibody (ABIN952082) Immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach t...
Western Blotting (WB) image for anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) (AA 467-495), (Middle Region) antibody (ABIN952082) Western blot analysis of Endoplasmin / HSP90B1 / TRA1 Antibody (Center) in K562, A549...
Background publications Suzuki, Kulkarni: "Extracellular heat shock protein HSP90beta secreted by MG63 osteosarcoma cells inhibits activation of latent TGF-beta1." in: Biochemical and biophysical research communications, Vol. 398, Issue 3, pp. 525-31, 2010 (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).