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FAIM antibody (Fas Apoptotic Inhibitory Molecule) (AA 64-93)

Details for Product anti-FAIM Antibody No. ABIN952160, Supplier: Log in to see
Antigen
  • FAIM
  • faim
  • FAIM1
  • EG623459
Epitope
AA 64-93, Middle Region
31
15
10
6
3
2
2
1
Reactivity
Human
85
40
36
7
2
1
1
1
1
1
Host
Rabbit
65
22
Clonality
Polyclonal
Conjugate
This FAIM antibody is un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
71
44
21
11
10
2
1
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 64-93 amino acids from the Central region of human FAIM.
Isotype Ig
Specificity This antibody recognizes Human FAIM (Center).
Purification Affinity Chromatography on Protein A
Alternative Name FAIM (FAIM Antibody Abstract)
Background FAIM plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells (By similarity).Synonyms: FAIM-1, FAIM1, Fas Apoptotic Inhibitory Molecule 1
Molecular Weight 20215 Da
Gene ID 55179
NCBI Accession NP_001028202
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-FAIM antibody (Fas Apoptotic Inhibitory Molecule) (AA 64-93) (ABIN952160) Western blot analysis of FAIM Antibody (Center) in HL-60 cell line lysates (35ug/lane...
Background publications Li, Qu, Meng et al.: "Crystallization and preliminary X-ray crystallographic studies of human FAIM protein." in: Acta crystallographica. Section F, Structural biology and crystallization communications, Vol. 66, Issue Pt 8, pp. 935-7, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

Kaku, Rothstein: "Fas apoptosis inhibitory molecule enhances CD40 signaling in B cells and augments the plasma cell compartment." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 3, pp. 1667-74, 2009 (PubMed).

Segura, Sole, Pascual et al.: "The long form of Fas apoptotic inhibitory molecule is expressed specifically in neurons and protects them against death receptor-triggered apoptosis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 42, pp. 11228-41, 2007 (PubMed).