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F-Box and Leucine-Rich Repeat Protein 5 (FBXL5) (AA 93-123), (N-Term) antibody

Details for Product No. ABIN952279, Supplier: Login to see
Antigen
  • fbxl5
  • MGC53238
  • FBXL5
  • FBL4
  • FBL5
  • FLR1
  • Fbl4
  • Fir4
  • wu:fb52d06
Epitope
AA 93-123, N-Term
15
15
4
4
2
2
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
56
21
14
1
Host
Rabbit
51
6
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
42
24
23
17
11
7
2
Supplier
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Immunogen KLH conjugated synthetic peptide between 93~123 amino acids from the N-terminal region of Human FBXL5.
Isotype Ig
Specificity This antibody recognizes Human and Mouse FBXL5 (N-term).
Purification Affinity Chromatography on Protein A
Alternative Name FBXL5 (FBXL5 Antibody Abstract)
Background Synonyms: F-box and leucine-rich repeat protein 5, F-box protein FBL4/FBL5, FBL4, FBL5, FLR1, p45SKP2-like protein
Molecular Weight 78,555 Da
Gene ID 26234
NCBI Accession NP_001180463
Research Area Proteolysis / Ubiquitin
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-F-Box and Leucine-Rich Repeat Protein 5 (FBXL5) (AA 93-123), (N-Term) antibody (ABIN952279) Flow cytometric analysis of HepG2 cells using FBXL5 Antibody (N-term) Cat.-No AP51622...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-F-Box and Leucine-Rich Repeat Protein 5 (FBXL5) (AA 93-123), (N-Term) antibody (ABIN952279) Immunohistochemistry in formalin fixed and paraffin embedded testis tissue reacted wi...
Western Blotting (WB) image for anti-F-Box and Leucine-Rich Repeat Protein 5 (FBXL5) (AA 93-123), (N-Term) antibody (ABIN952279) Western blot analysis of FBXL5 Antibody (N-term) Cat.-No AP51622PU-N in mouse heart t...
Background publications Salahudeen, Thompson, Ruiz et al.: "An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis." in: Science (New York, N.Y.), Vol. 326, Issue 5953, pp. 722-6, 2009 (PubMed).

Vashisht, Zumbrennen, Huang et al.: "Control of iron homeostasis by an iron-regulated ubiquitin ligase." in: Science (New York, N.Y.), Vol. 326, Issue 5953, pp. 718-21, 2009 (PubMed).

Zhang, Liu, Ding et al.: "FBXL5 interacts with p150Glued and regulates its ubiquitination." in: Biochemical and biophysical research communications, Vol. 359, Issue 1, pp. 34-9, 2007 (PubMed).

Ilyin, Rialland, Pigeon et al.: "cDNA cloning and expression analysis of new members of the mammalian F-box protein family." in: Genomics, Vol. 67, Issue 1, pp. 40-7, 2000 (PubMed).

Winston, Koepp, Zhu et al.: "A family of mammalian F-box proteins." in: Current biology : CB, Vol. 9, Issue 20, pp. 1180-2, 1999 (PubMed).

Cenciarelli, Chiaur, Guardavaccaro et al.: "Identification of a family of human F-box proteins." in: Current biology : CB, Vol. 9, Issue 20, pp. 1177-9, 1999 (PubMed).