Holocytochrome C Synthase (HCCS) (AA 179-209), (Middle Region) antibody

Details for Product No. ABIN952686, Supplier: Log in to see
Antigen
  • hccsb
  • id:ibd1278
  • wu:fb18h01
  • wu:fc64e12
  • wu:fi43e01
  • cchl
  • mcops7
  • DDBDRAFT_0217711
  • DDBDRAFT_0266707
  • DDB_0217711
  • DDB_0266707
  • CCHL
  • MCOPS7
  • RGD1563855
  • holocytochrome c synthase
  • cytochrome c heme-lyase
  • holocytochrome c synthase-like
  • holocytochrome c synthetase
  • hccs
  • cchl
  • HCCS
  • Hccs
  • LOC100356413
Epitope
AA 179-209, Middle Region
11
11
10
10
8
3
3
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
81
48
35
6
3
2
2
2
1
1
1
Host
Rabbit
71
10
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
61
36
31
13
12
9
9
3
3
2
1
Options
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Immunogen KLH conjugated synthetic peptide between 179~209 amino acids from the Central region of human HCCS / CCHL
Isotype Ig
Specificity This antibody recognizes Human and Mouse HCCS / CCHL (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name HCCS / CCHL (HCCS Antibody Abstract)
Background The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.Synonyms: Cytochrome c-type heme lyase, Holocytochrome c-type synthase
Molecular Weight 30602 Da
Gene ID 3052
NCBI Accession NP_001116080
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Holocytochrome C Synthase (HCCS) (AA 179-209), (Middle Region) antibody (ABIN952686) Immunohistochemistry analysis in formalin fixed and paraffin embedded colon carcinoma...
Western Blotting (WB) image for anti-Holocytochrome C Synthase (HCCS) (AA 179-209), (Middle Region) antibody (ABIN952686) Western blot analysis of HCCS / CCHL Antibody (Center) in mouse heart tissue lysates ...
Western Blotting (WB) image for anti-Holocytochrome C Synthase (HCCS) (AA 179-209), (Middle Region) antibody (ABIN952686) Western blot analysis of HCCS / CCHL Antibody (Center) in WiDr cell line lysates (35u...
Background publications Need, Attix, McEvoy, Cirulli, Linney, Hunt, Ge, Heinzen, Maia, Shianna, Weale, Cherkas, Clement, Spector, Gibson, Goldstein: "A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB." in: Human molecular genetics, Vol. 18, Issue 23, pp. 4650-61, 2009 (PubMed).

Nakashima-Kamimura, Asoh, Ishibashi, Mukai, Shidara, Oda, Munakata, Goto, Ohta: "MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction." in: Journal of cell science, Vol. 118, Issue Pt 22, pp. 5357-67, 2005 (PubMed).

Prakash, Cormier, McCall, Garcia, Sierra, Haupt, Zoghbi, Van Den Veyver: "Loss of holocytochrome c-type synthetase causes the male lethality of X-linked dominant microphthalmia with linear skin defects (MLS) syndrome." in: Human molecular genetics, Vol. 11, Issue 25, pp. 3237-48, 2002 (PubMed).