HSPBP1 antibody (N-Term)

Catalog No. ABIN952805

Product Details anti-HSPBP1 Antibody

Target: HSPBP1 (HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1))

Binding Specificity: AA 68-97, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human HSPBP1 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 68-97 amino acids from the N-terminal region of human HSPBP1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HSPBP1

Target: HSPBP1 (HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1))

Alternative Name: HSPBP1 (HSPBP1 Products)

Synonyms: FES1 antibody, 1500019G21Rik antibody, HSPA (Hsp70) binding protein 1 antibody, HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 antibody, HSPBP1 antibody, Hspbp1 antibody

Background: HSPBP1 inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.Synonyms: HSPBP, Heat shock protein-binding protein 1, Hsp70-binding protein 1, Hsp70-binding protein 2, Hsp70-interacting protein 1, Hsp70-interacting protein 2, HspBP2

Molecular Weight: 39474 Da

Gene ID: 23640

NCBI Accession: NP_001123578