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Interleukin 17a antibody (Middle Region)
IL17A
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Interleukin 17a Antibody
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Target
See all Interleukin 17a (IL17A) Antibodies
Interleukin 17a (IL17A)
(Interleukin 17A (IL17A))
Binding Specificity
All epitopes for Interleukin 17a antibodies
AA 60-87, Middle Region
Reactivity
All reactivities for Interleukin 17a antibodies
Human
Host
All hosts for Interleukin 17a antibodies
Rabbit
Clonality
All clonalities for Interleukin 17a antibodies
Polyclonal
Conjugate
All conjugates for Interleukin 17a antibodies
This Interleukin 17a antibody is un-conjugated
Application
All applications for Interleukin 17a antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Interleukin-17A (IL17A).
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Purified through a Protein A column followed by peptide affinity purification
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the central region (between 60-87aa) of human Interleukin-17A (IL17A).
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Interleukin 17a
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Target
Interleukin 17a (IL17A)
(Interleukin 17A (IL17A))
Alternative Name
Interleukin-17A (IL17A) (IL17A Products )
Synonyms
CTLA8 antibody, IL-17 antibody, IL-17A antibody, IL17 antibody, Ctla-8 antibody, Ctla8 antibody, Il17 antibody, ChIL-17 antibody, IL-17F antibody, IL17A antibody, CTLA-8 antibody, interleukin 17A antibody, IL17A antibody, Il17a antibody
Background
The protein encoded by the IL17A gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.Synonyms: CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17
Gene ID
3605
NCBI Accession
NP_002181
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