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INTS1 antibody (Integrator Complex Subunit 1) (N-Term)

Details for Product anti-INTS1 Antibody No. ABIN952931, Supplier: Log in to see
Antigen
  • 1110015K06Rik
  • DDBDRAFT_0218704
  • DDBDRAFT_0234073
  • DDB_0218704
  • DDB_0234073
  • fa14a05
  • INT1
  • INTS1
  • NET28
  • wu:fa14a05
  • wu:fa55a06
Epitope
N-Term
19
3
2
Reactivity
Human
25
2
1
Host
Rabbit
25
Clonality
Polyclonal
Conjugate
This INTS1 antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
21
16
2
2
1
Supplier
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Immunogen KLH conjugated synthetic peptide selected from the N-terminal region of Human INTS1
Isotype Ig
Specificity This antibody recognizes Human INTS1 (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name INTS1 (INTS1 Antibody Abstract)
Background INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).Synonyms: Int1, Integrator complex subunit 1, KIAA1440
Molecular Weight 244297 Da
Gene ID 26173
NCBI Accession NP_001073922
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-INTS1 antibody (Integrator Complex Subunit 1) (N-Term) (ABIN952931) Western blot analysis of INTS1 Antibody  in human placenta tissue lysates (35ug/lane)...
Background publications Nusbaum, Mikkelsen, Zody, Asakawa, Taudien, Garber, Kodira, Schueler, Shimizu, Whittaker, Chang, Cuomo, Dewar, FitzGerald, Yang, Allen, Anderson, Asakawa, Blechschmidt, Bloom, Borowsky, Butler, Cook et al.: "DNA sequence and analysis of human chromosome 8. ..." in: Nature, Vol. 439, Issue 7074, pp. 331-5, 2006 (PubMed).

Baillat, Hakimi, Näär, Shilatifard, Cooch, Shiekhattar: "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II." in: Cell, Vol. 123, Issue 2, pp. 265-76, 2005 (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).