IRF4 antibody (Middle Region)
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- Target See all IRF4 Antibodies
- IRF4 (Interferon Regulatory Factor 4 (IRF4))
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Binding Specificity
- AA 171-199, Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IRF4 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- Specificity
- This antibody recognizes Human IRF4 (Center).
- Purification
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- Immunogen
- KLH conjugated synthetic peptide between 171-199 amino acids from the Central region of human IRF4
- Isotype
- Ig Fraction
- Top Product
- Discover our top product IRF4 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- IRF4 (Interferon Regulatory Factor 4 (IRF4))
- Alternative Name
- IRF4 (IRF4 Products)
- Synonyms
- LSIRF antibody, MUM1 antibody, NF-EM5 antibody, AI385587 antibody, IRF-4 antibody, Spip antibody, IRF4 antibody, si:ch73-170d1.2 antibody, irf4 antibody, interferon regulatory factor 4 antibody, interferon regulatory factor 4a antibody, Interferon regulatory factor 4 antibody, PWWP domain-containing protein MUM1 antibody, IRF4 antibody, Irf4 antibody, irf4a antibody, irf4 antibody, LOC612320 antibody, LOC100068881 antibody
- Background
- The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.Synonyms: Interferon regulatory factor 4, LSIRF, Lymphocyte-specific interferon regulatory factor, MUM1, Multiple myeloma oncogene 1, NF-EM5
- Molecular Weight
- 51772 Da
- Gene ID
- 3662
- NCBI Accession
- NP_001182215
- Pathways
- Chromatin Binding
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