ISL1 antibody (Middle Region)
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- Target See all ISL1 Antibodies
- ISL1 (ISL LIM Homeobox 1 (ISL1))
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Binding Specificity
- AA 155-185, Middle Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ISL1 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody recognizes Human and Mouse Islet-1 / ISL1 (Center).
- Purification
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 155-185 amino acids from the Central region of human Islet-1 / ISL1
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ISL1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- ISL1 (ISL LIM Homeobox 1 (ISL1))
- Alternative Name
- Islet-1 / ISL1 (ISL1 Products)
- Synonyms
- Xisl-1 antibody, Xislet-1 antibody, islet1 antibody, ISLET-1 antibody, ISLET1 antibody, Isl-1 antibody, islet-1 antibody, isl-1=homeobox antibody, Islet-1 antibody, ISL LIM homeobox 1 S homeolog antibody, ISL LIM homeobox 1 antibody, ISL1 transcription factor, LIM/homeodomain antibody, isl1.S antibody, ISL1 antibody, Isl1 antibody, isl1 antibody
- Background
- ISL1 is a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.Synonyms: Insulin gene enhancer protein ISL-1
- Molecular Weight
- 39036 Da
- Gene ID
- 3670
- NCBI Accession
- NP_002193
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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