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LASP1 antibody (LIM and SH3 Protein 1) (AA 119-148)

Details for Product anti-LASP1 Antibody No. ABIN953141, Supplier: Log in to see
Antigen
  • AA408629
  • Def-4
  • fb92f05
  • lasp-1
  • Lasp-1
  • lasp1
  • LASP1
  • MGC53336
  • MGC89667
  • mln50
  • MLN50
  • SH3P6
  • Tg(Col1a1-lacZ)1Ngma
  • wu:fb92f05
  • zgc:77542
Epitope
AA 119-148, Middle Region
32
23
16
13
9
6
2
2
2
2
2
1
1
1
Reactivity
Human
106
22
21
10
6
5
4
4
2
2
1
Host
Rabbit
55
40
11
Clonality
Polyclonal
Conjugate
This LASP1 antibody is un-conjugated
5
5
5
5
5
5
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
100
58
13
7
7
3
2
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of Human LASP1
Isotype Ig
Specificity This antibody recognizes Human LASP1 (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name LASP1 (LASP1 Antibody Abstract)
Background This gene encodes a member of a LIM protein subfamily characterized by a LIM motif and a domain of Src homology region 3. The encoded protein functions as an actin-binding protein and possibly in cytoskeletal organization.Synonyms: LASP-1, LIM and SH3 domain protein 1, MLN50
Molecular Weight 29717 Da
Gene ID 3927
NCBI Accession NP_006139
Research Area Signaling, Cytoskeleton, Microfilaments
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-LASP1 antibody (LIM and SH3 Protein 1) (AA 119-148) (ABIN953141) Western blot analysis of LASP1 Antibody (Center) in A549 cell line lysates (35ug/lane...
Background publications Traenka, Remke, Korshunov, Bender, Hielscher, Northcott, Witt, Ryzhova, Felsberg, Benner, Riester, Scheurlen, Grunewald, von Deimling, Kulozik, Reifenberger, Taylor, Lichter, Butt, Pfister: "Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma." in: Cancer research, Vol. 70, Issue 20, pp. 8003-14, 2010 (PubMed).

Zhao, Wang, Sun, Ding: "Comparative proteomic analysis identifies proteins associated with the development and progression of colorectal carcinoma." in: The FEBS journal, Vol. 277, Issue 20, pp. 4195-204, 2010 (PubMed).

Alm, Scholz, Kultima, Nilsson, Andrén, Savitski, Bergman, Stigson, Fex-Svenningsen, Dencker: "In vitro neurotoxicity of PBDE-99: immediate and concentration-dependent effects on protein expression in cerebral cortex cells." in: Journal of proteome research, Vol. 9, Issue 3, pp. 1226-35, 2010 (PubMed).

Frietsch, Grunewald, Jasper, Kammerer, Herterich, Kapp, Honig, Butt: "Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer." in: British journal of cancer, Vol. 102, Issue 11, pp. 1645-53, 2010 (PubMed).