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MINPP1 antibody (an enzyme that removes 3-phosphate from inositol phosphate substrates.") (AA 35-63)

Details for Product anti-MINPP1 Antibody No. ABIN953449, Supplier: Log in to see
Antigen
  • minpp1
  • zgc:56080
  • zgc:76991
  • HIPER1
  • AA408516
  • MINPP2
  • MIPP
Epitope
AA 35-63, N-Term
20
16
15
12
4
4
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
70
12
11
Host
Rabbit
68
2
Clonality
Polyclonal
Conjugate
This MINPP1 antibody is un-conjugated
7
6
6
4
4
4
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
62
45
31
23
5
3
2
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 35-63 amino acids from the N-terminal region of Human MINPP1
Isotype Ig
Specificity This antibody recognizes Human MINPP1 (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name MINPP1 (MINPP1 Antibody Abstract)
Background This gene encodes multiple inositol polyphosphate phosphatase, an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate, an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.Synonyms: 3, 4, 5)-tetrakisphosphate 3-phosphatase, 5)P(4) 3-phosphatase, Inositol (1, Ins(1, MIPP, Multiple inositol polyphosphate phosphatase 1, UNQ900/PRO1917
Molecular Weight 55051 Da
Gene ID 9562
NCBI Accession NP_001171588
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-MINPP1 antibody (an enzyme that removes 3-phosphate from inositol phosphate substrates. Flow cytometric analysis of K562 cells using MINPP1 Antibody (N-term) Cat.-No AP52700...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-MINPP1 antibody (an enzyme that removes 3-phosphate from inositol phosphate substrates. Immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocar...
Western Blotting (WB) image for anti-MINPP1 antibody (an enzyme that removes 3-phosphate from inositol phosphate substrates. Western blot analysis of MINPP1 Antibody (N-term) Cat.-No AP52700PU-N in K562 cell li...
Western Blotting (WB) image for anti-MINPP1 antibody (an enzyme that removes 3-phosphate from inositol phosphate substrates. Western blot analysis of MINPP1 Antibody (N-term) in murine erythroleukemia cell line...
Background publications Newman, Walter, Lunetta et al.: "A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium." in: The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 65, Issue 5, pp. 478-87, 2010 (PubMed).

Cho, King, Qian et al.: "Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 16, pp. 5998-6003, 2008 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. ..." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).