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MOB1A antibody (N-Term)
MOBKL1B
Reactivity: Human
WB, FACS, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MOB1A Antibody
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Target
See all MOB1A (MOBKL1B) Antibodies
MOB1A (MOBKL1B)
(MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
Binding Specificity
All epitopes for MOB1A antibodies
AA 4-33, N-Term
Reactivity
All reactivities for MOB1A antibodies
Human
Host
All hosts for MOB1A antibodies
Rabbit
Clonality
All clonalities for MOB1A antibodies
Polyclonal
Conjugate
All conjugates for MOB1A antibodies
This MOB1A antibody is un-conjugated
Application
All applications for MOB1A antibodies
Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human MOBKL1B (N-term).
Purification
Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen
KLH conjugated synthetic peptide between 4-33 amino acids from the N-terminal region of Human MOBKL1B
Isotype
Ig Fraction
Top Product
Discover our top product MOBKL1B Primary Antibody
Alternatives
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anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (AA 167-216) antibody
MOBKL1B
Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Monkey, Pig, Bat
WB, IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for MOB1A
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Target
MOB1A (MOBKL1B)
(MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
Alternative Name
MOBKL1B (MOBKL1B Products )
Synonyms
mob1 antibody, mob4b antibody, MOB1A antibody, MOBK1B antibody, MOB1 antibody, mats1 antibody, mobk1b antibody, mobkl1b antibody, MOBKL1B antibody, wu:fv69d04 antibody, zgc:56189 antibody, C2orf6 antibody, MATS1 antibody, Mob4B antibody, 4022402H07Rik antibody, MOB4B antibody, Mobk1b antibody, Mobkl1b antibody, MOB kinase activator 1A L homeolog antibody, MOB kinase activator 1A antibody, MOB kinase activator 1A pseudogene antibody, mob1a.L antibody, MOB1A antibody, mob1a antibody, LOC712156 antibody, Mob1a antibody
Background
Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L.Synonyms: C2orf6, MOB4B, MOBK1B, Mob1 alpha, Mob1 homolog 1B, Mps one binder kinase activator-like 1B, Protein Mob4B
Molecular Weight
25080 Da
Gene ID
55233
NCBI Accession
NP_060691
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