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MTA3 antibody (Metastasis Associated 1 Family, Member 3) (C-Term)

Details for Product anti-MTA3 Antibody No. ABIN953531, Supplier: Login to see
Antigen
  • MTA3
  • DKFZp468E247
  • 1110002J22Rik
  • mKIAA1266
Epitope
C-Term, AA 558-587
20
15
6
5
3
2
2
1
1
1
1
Reactivity
Human
56
11
7
2
2
2
Host
Rabbit
43
13
Clonality
Polyclonal
Conjugate
This MTA3 antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
43
25
9
7
3
2
2
2
Supplier
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Immunogen Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 558-587aa) of human MTA3.
Isotype Ig
Specificity This antibody recognizes human MTA3 at C-term.
Purification Purified through a Protein A column followed by peptide affinity purification
Alternative Name MTA3 (MTA3 Antibody Abstract)
Background MTA3 plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels.Synonyms: KIAA1266, Metastasis-associated protein MTA3
Molecular Weight 67504 Da
Gene ID 57504
NCBI Accession NP_065795
Research Area Cancer, Transcription Factors
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-MTA3 antibody (Metastasis Associated 1 Family, Member 3) (C-Term) (ABIN953531) Western blot analysis in Ramos cell line lysates (35ug/lane) using MTA3 Antibody (C-t...
Background publications Brüning, Makovitzky, Gingelmaier et al.: "The metastasis-associated genes MTA1 and MTA3 are abundantly expressed in human placenta and chorionic carcinoma cells." in: Histochemistry and cell biology, Vol. 132, Issue 1, pp. 33-8, 2009 (PubMed).

Lasky-Su, Neale, Franke et al.: "Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 8, pp. 1345-54, 2008 (PubMed).

Zhang, Singh, Talukder et al.: "Metastatic tumor antigen 3 is a direct corepressor of the Wnt4 pathway." in: Genes & development, Vol. 20, Issue 21, pp. 2943-8, 2006 (PubMed).

Yu, Hsu, Chen et al.: "Breast cancer risk associated with genotypic polymorphism of the genes involved in the estrogen-receptor-signaling pathway: a multigenic study on cancer susceptibility." in: Journal of biomedical science, Vol. 13, Issue 3, pp. 419-32, 2006 (PubMed).

Fujita, Jaye, Geigerman et al.: "MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation." in: Cell, Vol. 119, Issue 1, pp. 75-86, 2004 (PubMed).