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COBRA1 antibody (Middle Region)
COBRA1
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-COBRA1 Antibody
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Target
See all COBRA1 Antibodies
COBRA1
(Cofactor of BRCA1 (COBRA1))
Binding Specificity
All epitopes for COBRA1 antibodies
AA 255-285, Middle Region
Reactivity
All reactivities for COBRA1 antibodies
Human
Host
All hosts for COBRA1 antibodies
Rabbit
Clonality
All clonalities for COBRA1 antibodies
Polyclonal
Conjugate
All conjugates for COBRA1 antibodies
This COBRA1 antibody is un-conjugated
Application
All applications for COBRA1 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to COBRA1.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Affinity chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 255-285 amino acids from the Central region of human COBRA1
Isotype
Ig Fraction
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Discover our top product COBRA1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for COBRA1
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Target
COBRA1
(Cofactor of BRCA1 (COBRA1))
Alternative Name
NELF-B (COBRA1 Products )
Synonyms
LOC100219583 antibody, COBRA1 antibody, NELF-B antibody, bZ1O1.4 antibody, cobra1 antibody, cobra2 antibody, fe01e12 antibody, wu:fe01e12 antibody, zgc:55628 antibody, MGC131073 antibody, Cobra1 antibody, RGD1307832 antibody, A730008L03Rik antibody, AB041607 antibody, AI663983 antibody, Nelf-b antibody, cofactor of BRCA1 antibody, negative elongation factor complex member B antibody, negative elongation factor complex member B L homeolog antibody, LOC100219583 antibody, NELFB antibody, nelfb antibody, nelfb.L antibody, Nelfb antibody
Background
NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2, MIM 606026), either NELFC or NELFD (TH1L, MIM 605297), and NELFE (RDBP, MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1, MIM 603555) and SPT5 (SUPT5H, MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).Synonyms: COBRA1, Cofactor of BRCA1, KIAA1182, NELFB, Negative elongation factor B
Molecular Weight
65697 Da
Gene ID
25920
NCBI Accession
NP_056271
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