You are viewing an incomplete version of our website. Please click to reload the website as full version.

Hypocretin (Orexin) Receptor 1 (HCRTR1) (AA 269-298), (Middle Region) antibody

Details for Product No. ABIN953936, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms HCRTR1, OX1R, Ox1r, Hctr1
Middle Region, AA 269-298
(25), (15), (12), (11), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
(78), (29), (24), (4), (3), (2), (1), (1)
(75), (8)
(2), (2), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(51), (41), (20), (7), (5), (2), (1)
Pubmed 5 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 269-298 amino acids from the Central region of Human Orexin receptor type 1 (Center) Genename: HCRTR1
Isotype Ig
Specificity This antibody recognizes Human Orexin receptor type 1 (Center)
Purification Protein A column, followed by peptide affinity purification
Alternative Name Orexin Receptor Type 1 (HCRTR1 Antibody Abstract)
Background The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.Synonyms: HCRTR1, Hypocretin receptor type 1, Ox1r
Molecular Weight 47536 Da
Gene ID 3061
NCBI Accession NP_001516
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Hypocretin (Orexin) Receptor 1 (HCRTR1) (AA 269-298), (Middle Region) antibody (ABIN953936) Western blot analysis of Orexin receptor type 1 Antibody (Center) in NCI-H292 cell li...
Background publications Peltonen, Akerman, Bart: "A role for PKD1 and PKD3 activation in modulation of calcium oscillations induced by orexin receptor 1 stimulation." in: Biochimica et biophysica acta, Vol. 1803, Issue 10, pp. 1206-12, 2010 (PubMed).

Pinheiro, Bulik, Thornton et al.: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010 (PubMed).

Saus, Brunet, Armengol et al.: "Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients." in: Journal of psychiatric research, Vol. 44, Issue 14, pp. 971-8, 2010 (PubMed).

Turunen, Ekholm, Somerharju et al.: "Arachidonic acid release mediated by OX1 orexin receptors." in: British journal of pharmacology, Vol. 159, Issue 1, pp. 212-21, 2010 (PubMed).

El Firar, Voisin, Rouyer-Fessard et al.: "Discovery of a functional immunoreceptor tyrosine-based switch motif in a 7-transmembrane-spanning receptor: role in the orexin receptor OX1R-driven apoptosis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 12, pp. 4069-80, 2009 (PubMed).

Catalog No. ABIN953936
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)