KAT2B antibody (N-Term)

Catalog No. ABIN954022

Product Details anti-KAT2B Antibody

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Binding Specificity: AA 260-291, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT2B antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to PCAF.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide between 260-291 amino acids from the N-terminal region of human PCAF

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KAT2B

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Alternative Name: PCAF / KAT2B (KAT2B Products)

Synonyms: PCAF antibody, pcaf antibody, si:ch211-1j13.2 antibody, zgc:161980 antibody, gb:dq017634 antibody, im:7156024 antibody, CAF antibody, P antibody, P/CAF antibody, A930006P13Rik antibody, AI461839 antibody, AW536563 antibody, Pcaf antibody, p/CAF antibody, lysine acetyltransferase 2B antibody, K(lysine) acetyltransferase 2B antibody, K(lysine) acetyltransferase 2A antibody, KAT2B antibody, kat2b antibody, kat2a antibody, Kat2b antibody

Background: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.Synonyms: Histone acetylase PCAF, Histone acetyltransferase KAT2B, Histone acetyltransferase PCAF, Lysine acetyltransferase 2B, P/CAF, P300/CBP-associated factor

Molecular Weight: 93013 Da

Gene ID: 8850

NCBI Accession: NP_003875

Pathways: p53 Signaling, Regulation of Carbohydrate Metabolic Process