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PCDHGA1 antibody (Middle Region)

PCDHGA1 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN954047
  • Target See all PCDHGA1 Antibodies
    PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    AA 294-323, Middle Region
    Reactivity
    • 15
    • 1
    Human
    Host
    • 13
    • 3
    Rabbit
    Clonality
    • 13
    • 3
    Polyclonal
    Conjugate
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    This PCDHGA1 antibody is un-conjugated
    Application
    • 16
    • 14
    • 13
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Human PCDHGA1 (Center).
    Purification
    Protein A column, followed by peptide affinity purification
    Immunogen
    KLH conjugated synthetic peptide between 294-323 amino acids from the Central region of human PCDHGA1
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PCDHGA1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))
    Alternative Name
    PCDHGA1 (PCDHGA1 Products)
    Synonyms
    PCDH-GAMMA-A1 antibody, protocadherin gamma subfamily A, 1 antibody, protocadherin gamma-C5 antibody, PCDHGA1 antibody, LOC478038 antibody, Pcdhga1 antibody
    Background
    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.Synonyms: PCDH-gamma-A1, Protocadherin gamma-A1
    Molecular Weight
    90kd
    Gene ID
    56114
    NCBI Accession
    NP_061735
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