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Platelets antibody

Reactivity: Mouse FACS, Func Host: Rat Monoclonal AIP21 unconjugated
Catalog No. ABIN954180
  • Target
    Platelets
    Reactivity
    • 2
    • 2
    • 1
    Mouse
    Host
    • 3
    • 2
    Rat
    Clonality
    • 5
    Monoclonal
    Conjugate
    • 4
    • 1
    Un-conjugated
    Application
    • 3
    • 2
    • 2
    Flow Cytometry (FACS), Functional Studies (Func)
    Purification
    Affinity Chromatography.
    Clone
    AIP21
    Isotype
    IgM
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Platelets
    Background
    Platelets or thrombocytes are the blood cell fragments that are involved in the cellular mechanisms that lead to the formation of blood clots. Low levels or dysfunction predisposes for bleeding, while high levels, although usually asymptomatic, may increase the risk of thrombosis. Like red blood cells, platelets are anuclear (no cell nucleus) and discoid (disc shaped), they measure 1.5 to 3.0 μm in diameter. The body has a very limited reserve of platelets, so they can be rapidly depleted. They contain RNA, a canalicular system, and several different types of granules, lysosomes (containing acid hydrolases), dense bodies (containing ADP, ATP serotonin and calcium) and alpha granules (containing fibrinogen, factor V, vitronectin, thrombospondin and von Willebrand factor), the contents of which are released upon activation of the platelet. These granule contents play an important role in both hemostasis and in the inflammatory response.
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