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Phospholipase C beta 1 antibody (phospholipase C, beta 1 (phosphoinositide-Specific)) (C-Term)

Details for Product anti-PLCB1 Antibody No. ABIN954182, Supplier: Login to see
Antigen
  • PLCB1
  • 3110043I21Rik
  • AI132408
  • Plcb
  • mKIAA0581
  • EIEE12
  • PI-PLC
  • PLC-154
  • PLC-I
  • PLC154
  • PLCB1A
  • PLCB1B
  • PLC'1
  • PLCbeta1
  • Phosphb
  • RATPHOSPHB
Alternatives
anti-Human Phospholipase C beta 1 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
C-Term, AA 1155-1184
10
3
2
2
1
1
1
1
1
1
Reactivity
Human
38
26
20
3
Host
Rabbit
37
5
1
Clonality
Polyclonal
Conjugate
This Phospholipase C beta 1 antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
28
10
7
6
4
4
3
3
Supplier
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Immunogen KLH conjugated synthetic peptide between 1155~1184 amino acids from the C-terminal region of human PLCB1
Isotype Ig
Specificity This antibody recognizes Human PLCB1 (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name PLCB1 (PLCB1 Antibody Abstract)
Background The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta-1, KIAA0581, PLC beta1, PLC-I, PLC-beta-1, Phosphoinositide phospholipase C-beta-1, Phospholipase C-I, Phospholipase C-beta-1
Molecular Weight 138567 Da
Gene ID 23236
NCBI Accession NP_056007
Pathways WNT Signaling, AMPK Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Phospholipase C beta 1 antibody (phospholipase C, beta 1 (phosphoinositide-Specific)) (C-Term) (ABIN954182) Flow cytometric analysis of HL-60 cells using PLCB1 Antibody (C-term) Cat.-No AP53333...
Western Blotting (WB) image for anti-Phospholipase C beta 1 antibody (phospholipase C, beta 1 (phosphoinositide-Specific)) (C-Term) (ABIN954182) Western blot analysis of PLCB1 Antibody (C-term) in HL-60 cell line lysates (35ug/lan...
Background publications Need, Attix, McEvoy et al.: "A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB." in: Human molecular genetics, Vol. 18, Issue 23, pp. 4650-61, 2009 (PubMed).

Woodcock, Grubb, Filtz et al.: "Selective activation of the \b\" splice variant of phospholipase Cbeta1 in chronically dilated human and mouse atria."" in: Journal of molecular and cellular cardiology, Vol. 47, Issue 5, pp. 676-83, 2009 (PubMed).

Zhang, Kwon, Vogel et al.: "PI(3,4,5)P3 potentiates phospholipase C-beta activity." in: Journal of receptor and signal transduction research, Vol. 29, Issue 1, pp. 52-62, 2009 (PubMed).