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phospholipase C, delta 1 (PLCD1) (N-Term), (AA 154-184) antibody

Details for Product No. ABIN954185
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Antigen
Synonyms NDNC3, PLC-III, AW212592, C79986, Plc1
Epitope
N-Term, AA 154-184
(11), (7), (1), (1), (1), (1)
Reactivity
Human
(17), (4), (4), (2), (2), (2)
Host
Rabbit
(18), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(18), (9), (1), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

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Catalog No. ABIN954185
357.50 $
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Immunogen KLH conjugated synthetic peptide between 154-184 amino acids from the N-terminal region of human PLCD1
Specificity This antibody recognizes Human PLCD1 (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name PLCD1
Background Phosphoinositide-specific phospholipase C (PLC) acts as a signal transducer that generates 2 second messengers, diacylglycerol and inositol 1,4,5-trisphosphate, by hydrolyzing inositol phospholipids. PLC comprises a diverse family of enzymes that differ in structure and tissue distribution (Berridge, 1993 [PubMed 8381210]).
Alternate names: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase delta-1, PLC-III, PLC-delta-1, Phosphoinositide phospholipase C-delta-1, Phospholipase C delta 1, Phospholipase C-III, Phospholipase C-delta-1
Molecular Weight 85665 Da
Gene ID 5333
NCBI Accession NP_001124436
Research Area Signaling
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Godin, Ferreira, Dale et al.: "The small GTPase Ral couples the angiotensin II type 1 receptor to the activation of phospholipase C-delta 1." in: Molecular pharmacology, Vol. 77, Issue 3, pp. 388-95, 2010 (PubMed).

Segat, Brandão, Guimarães et al.: "Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment." in: Vaccine, Vol. 28, Issue 10, pp. 2201-6, 2010 (PubMed).

Saus, Brunet, Armengol et al.: "Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients." in: Journal of psychiatric research, Vol. 44, Issue 14, pp. 971-8, 2010 (PubMed).

Guo, Golebiewska, DAmico et al.: "The small G protein Rac1 activates phospholipase Cdelta1 through phospholipase Cbeta2." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24999-5008, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

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