RCBTB1 antibody (Regulator of Chromosome Condensation (RCC1) and BTB (POZ) Domain Containing Protein 1) (AA 349-377)

Details for Product anti-RCBTB1 Antibody No. ABIN954490, Supplier: Log in to see
Antigen
  • fj43a07
  • zgc:56037
  • wu:fj43a07
  • MGC81035
  • rcbtb1
  • CLLD7
  • CLLL7
  • GLP
  • RP11-185C18.1
  • 5430409I18Rik
  • AW111883
  • regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
  • Rcbtb1
  • RCBTB1
  • rcbtb1
Epitope
AA 349-377, Middle Region
13
10
9
8
2
2
1
1
1
1
1
1
Reactivity
Human
74
46
35
3
3
3
2
2
2
2
2
1
1
1
Host
Rabbit
70
4
Clonality
Polyclonal
Conjugate
This RCBTB1 antibody is un-conjugated
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
46
26
23
10
8
2
2
Options
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Immunogen KLH conjugated synthetic peptide between 349-377 amino acids from the Central region of Human RCBTB1. Genename: RCBTB1
Isotype Ig
Specificity This antibody recognizes Human RCBTB1 (Center).
Purification Affinity Chromatography on Protein A
Alternative Name RCBTB1 (RCBTB1 Antibody Abstract)
Background This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.Synonyms: CLL deletion region gene 7 protein, CLLD7, Chronic lymphocytic leukemia deletion region gene 7 protein, RCC1 and BTB domain-containing protein 1, Regulator of chromosome condensation and BTB domain-containing protein 1
Molecular Weight 58252 Da
Gene ID 55213
NCBI Accession NP_060661
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-RCBTB1 antibody (Regulator of Chromosome Condensation (RCC1) and BTB (POZ) Domain Containing Protein 1) (AA 349-377) (ABIN954490) Western blot analysis of RCBTB1 Antibody  in 293 cell line lysates (35ug/lane). This ...
Background publications Genuneit, Cantelmo, Weinmayr, Wong, Cooper, Riikjärv, Gotua, Kabesch, von Mutius, Forastiere, Crane, Nystad, El-Sharif, Batlles-Garrido, García-Marcos, García-Hernández, Morales-Suarez-Varela, Nilsson, Bråbäck, Saraçlar, Weiland, Cookson, Strachan, Moffat: "A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2." in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Vol. 39, Issue 12, pp. 1875-88, 2010 (PubMed).

Guo, Tardif, Ghelima, Chan, Ingelfinger, Chen, Chenier: "A novel angiotensin II type 1 receptor-associated protein induces cellular hypertrophy in rat vascular smooth muscle and renal proximal tubular cells." in: The Journal of biological chemistry, Vol. 279, Issue 20, pp. 21109-20, 2004 (PubMed).

Dunham, Matthews, Burton, Ashurst, Howe, Ashcroft, Beare, Burford, Hunt, Griffiths-Jones, Jones, Keenan, Oliver, Scott, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey et al.: "The DNA sequence and analysis of human chromosome 13. ..." in: Nature, Vol. 428, Issue 6982, pp. 522-8, 2004 (PubMed).