Peropsin (RRH) (C-Term), (AA 212-240) antibody

Details for Product No. ABIN954631
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Antigen
Epitope
C-Term, AA 212-240
(8), (7), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(22), (1)
Host
Rabbit
(23)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(18), (13), (4), (2)
Pubmed 4 references available
Quantity 0.4 mL
Shipping to United States (Change)
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Catalog No. ABIN954631
357.50 $
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Immunogen KLH conjugated synthetic peptide between 212-240 amino acids from the C-terminal region of Human RRH Genename: RRH
Specificity Recognizes RRH C-term).
Purification Protein A column followed by peptide Affinity purification
Alternative Name RRH
Background Peropsin is a visual pigment-like protein identified following large-scale sequencing of cDNAs derived from human ocular tissues. Peropsin mRNA is found in the retinal pigment epithelium (RPE) of the eye. Peropsin immunoreactivity, localizes the protein to the apical face of the RPE, and most prominently to the microvilli that surround the photoreceptor outer segments. It is thought that Peropsin may play a role in RPE physiology either in light detection as well as monitoring the concentration of retinoids (or other photoreceptor- derived compounds). It may play a role in retinal pigement epithelium physiology either by detecting light directly or by monitoring the concentration of retinoids or other photoreceptor-derived compounds.
Alternate names: Peropsin, Visual pigment-like receptor peropsin
Gene ID 10692
NCBI Accession NP_006574
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Barrios-Rodiles, Brown, Ozdamar et al.: "High-throughput mapping of a dynamic signaling network in mammalian cells." in: Science (New York, N.Y.), Vol. 307, Issue 5715, pp. 1621-5, 2005 (PubMed).

Cai, Del Priore: "Gene expression profile of cultured adult compared to immortalized human RPE." in: Molecular vision, Vol. 12, pp. 1-14, 2006 (PubMed).

Luttrell: "Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors." in: Molecular biotechnology, Vol. 39, Issue 3, pp. 239-64, 2008 (PubMed).

Kalsi, Kuo, Aliev et al.: "A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts." in: Human molecular genetics, Vol. 19, Issue 12, pp. 2497-506, 2010 (PubMed).

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