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Septin 2 (SEPT2) (C-Term), (AA 279-309) antibody

Details for Product No. ABIN954726
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Antigen
Synonyms
SEPT2, sept2, Septin-2B, diff6, hnedd5, nedd5, pnutl3, sept2-B, Septin-2, DIFF6, NEDD5, Pnutl3, hNedd5, AW208991, Nedd-5, Nedd5, mKIAA0158, Vesp11, wu:fb52g01, wu:fb99a01, Septin-2A, Septin-A, septa,  ... show more
SEPT2, sept2, Septin-2B, diff6, hnedd5, nedd5, pnutl3, sept2-B, Septin-2, DIFF6, NEDD5, Pnutl3, hNedd5, AW208991, Nedd-5, Nedd5, mKIAA0158, Vesp11, wu:fb52g01, wu:fb99a01, Septin-2A, Septin-A, septa, xlsepta, Sep-02 show less
Epitope
C-Term, AA 279-309
(9), (8), (7), (7), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(67), (34), (33), (17), (12), (12), (4), (2), (2), (2)
Host
Rabbit
(54), (11), (7)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(57), (34), (10), (8), (8), (7), (4), (1)
Pubmed 4 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN954726
357.50 $
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Immunogen KLH conjugated synthetic peptide between 279-309 amino acids from the C-terminal region of Human SEPT2 Genename: SEPT2
Specificity Recognizes SEPT2 (C-term).
Purification Protein A column followed by peptide Affinity purification
Alternative Name Septin-2
Background Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
Alternate names: DIFF6, KIAA0158, NEDD-5, NEDD5, Neural precursor cell expressed developmentally down- regulated protein 5, SEPT-2, SEPT2, Septin2
Gene ID 4735
NCBI Accession NP_001008491
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Shen, Vermeulen, Rajaraman et al.: "Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China." in: Environmental and molecular mutagenesis, Vol. 50, Issue 4, pp. 285-90, 2009 (PubMed).

Mostowy, Danckaert, Tham et al.: "Septin 11 restricts InlB-mediated invasion by Listeria." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11613-21, 2009 (PubMed).

Hosgood, Menashe, He et al.: "PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, 2009 (PubMed).

Guey, García-Closas, Murta-Nascimento et al.: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, 2010 (PubMed).

Validation Images
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