SIK1 antibody (AA 1-101)
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- Target See all SIK1 Antibodies
- SIK1 (Salt-Inducible Kinase 1 (SIK1))
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Binding Specificity
- AA 1-101
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SIK1 antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificity
- Recognizes Human Snf1lk
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Purification
- Protein A Chromatography
- Immunogen
- SIK1 (AAH38504, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag.
- Clone
- 2C12
- Isotype
- IgG2a
- Top Product
- Discover our top product SIK1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS, pH 7.2
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- SIK1 (Salt-Inducible Kinase 1 (SIK1))
- Alternative Name
- SIK1 (SIK1 Products)
- Synonyms
- Msk antibody, Sik antibody, Snf1lk antibody, SIK2 antibody, SNF1LK antibody, MSK antibody, SIK antibody, salt-inducible kinase 1 antibody, salt inducible kinase 1 antibody, SIK1 antibody, Sik1 antibody
- Background
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.Synonyms: SIK, SIK-1, SNF1LK, Salt-inducible protein kinase 1, Serine/threonine-protein kinase SIK1, Serine/threonine-protein kinase SNF1-like kinase 1
- Gene ID
- 150094
- NCBI Accession
- NP_775490
- UniProt
- P57059
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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