SNX17 antibody (Sorting Nexin 17) (N-Term)

Details for Product anti-SNX17 Antibody No. ABIN954887, Supplier: Log in to see
Antigen
  • snx17
  • MGC53167
  • MGC69341
  • MGC198061
  • MGC83142
  • SNX17
  • wu:fb67g03
  • wu:fb67g09
  • wu:fc27g08
  • wu:fj81d04
  • si:ch211-101l18.2
  • 5830447M19Rik
  • AI790646
  • D5Ertd260e
  • mKIAA0064
  • sorting nexin 17
  • snx17
  • SNX17
  • LOC100351476
  • Snx17
Epitope
N-Term, AA 52-82
11
10
8
4
2
2
2
1
Reactivity
Human
34
3
3
Host
Rabbit
30
4
Clonality
Polyclonal
Conjugate
This SNX17 antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
32
20
3
2
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 52-82aa) of human SNX17.
Isotype Ig
Specificity This antibody detects human SNX17 at N-term.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Purified through a protein A column; followed by peptide affinity purification.
Alternative Name Sorting Nexin-17 (SNX17) (SNX17 Antibody Abstract)
Background The SNX17 gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin.Synonyms: KIAA0064
Gene ID 9784
NCBI Accession NP_055563
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-SNX17 antibody (Sorting Nexin 17) (N-Term) (ABIN954887) Western blot analysis in 293 cell line lysates (35ug/lane) using Sorting nexin-17 (SN...
Background publications Lee, Retamal, Cuitiño, Caruano-Yzermans, Shin, van Kerkhof, Marzolo, Bu: "Adaptor protein sorting nexin 17 regulates amyloid precursor protein trafficking and processing in the early endosomes." in: The Journal of biological chemistry, Vol. 283, Issue 17, pp. 11501-8, 2008 (PubMed).

Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, 2007 (PubMed).

Wu, Ma, Brown, Geisler, Li, Tzeng, Jia, Jurisica, Li: "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening." in: Proteomics, Vol. 7, Issue 11, pp. 1775-85, 2007 (PubMed).

Czubayko, Knauth, Schlüter, Florian, Bohnensack: "Sorting nexin 17, a non-self-assembling and a PtdIns(3)P high class affinity protein, interacts with the cerebral cavernous malformation related protein KRIT1." in: Biochemical and biophysical research communications, Vol. 345, Issue 3, pp. 1264-72, 2006 (PubMed).

van Kerkhof, Lee, McCormick, Tetrault, Lu, Schoenfish, Oorschot, Strous, Klumperman, Bu: "Sorting nexin 17 facilitates LRP recycling in the early endosome." in: The EMBO journal, Vol. 24, Issue 16, pp. 2851-61, 2005 (PubMed).